Screening of food supplements for toxic pyrrolizidine alkaloids
نویسندگان
چکیده
منابع مشابه
Toxic Behaviour of Naturally Occurring Pyrrolizidine Alkaloids
The Pyrrolizidine Alkaloids (PAs) are the chemicals which are found in various plant species throughout the world. Pyrrolizidine alkaloids (PAs) are secondary metabolites those have been evolved as a powerful means in the plant defensive system against herbivores. Several studies are being performing to detect presence of PAs in the food and feed which are obtained from plants through direct or...
متن کاملNon-toxic pyrrolizidine alkaloids from Eupatorium semialatum.
The leaves of Eupatorium semialatum were investigated for the occurrence of pyrrolizidine alkaloids. Although this type of alkaloids generally occurs in the Eupatorieae, only unusual non-toxic pyrrolizidines of the tussilagin type were identified. All compounds are methyl esters of the corresponding beta-amino acids.
متن کاملIdentification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism.
Pyrrolizidine Alkaloids (PAs) are currently one of the most important botanical hepatotoxic ingredients. Glutathion (GSH) metabolism is the most reported pathway involved in hepatotoxicity mechanism of PAs. We speculate that, for different PAs, there should be a common mechanism underlying their hepatotoxicity in GSH metabolism. Computational methods were adopted to test our hypothesis in consi...
متن کاملPyrrolizidine Alkaloids from Heliotropium
Investigation of the pyrrolizidine alkaloids of Heliotropium arbainense resulted in the isolation and identification of heliotrine, europine and 7-angelylheliotrine. From H. ovalifolium three alkaloids were isolated: supinine, 7-angelylheliotridine and an alkaloid which was shown to be of the heliotridine monoester type with a dehydrated viridifloric acid.
متن کاملCharacterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry.
The UHPLC-QToF-MS analysis of pyrrolizidine alkaloids (PAs) from various parts of 37 botanicals and 7 products was performed. A separation by LC was achieved using a reversed-phase column and a gradient of water/acetonitrile each containing formic acid as the mobile phase. MS-MS detection was used because of its high selectivity, and ability to provide structural information. Free base and N-ox...
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ژورنال
عنوان ژورنال: Journal of Consumer Protection and Food Safety
سال: 2020
ISSN: 1661-5751,1661-5867
DOI: 10.1007/s00003-020-01296-9